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GCSE History 05 — Changes in Medicine c1848–c1948

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Topics include Medicine in 1848: Barriers to Progress, Florence Nightingale and the Nursing Revolution, The Revolution in Pain Relief: Anaesthetics, The Fight Against Infection: Antiseptics to Asepsis, The Public Health Revolution (1848–1875), Germ Theory: Pasteur and Koch, Women in Medicine (c.1850–1918), and The Liberal Reforms (1906–1914).

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The Revolution in Pain Relief: Anaesthetics

The discovery of effective anaesthetics solved the problem of pain in surgery, though initially leading to higher infection rates.

Key points

  • Ether (1846): Used by Robert Liston. Effective but flammable and irritated the lungs.
  • Chloroform (1847): Discovered by James Simpson. It was more effective and easier to use but dosage was tricky.
  • Opposition: Religious objections (childbirth pain is natural) and medical fears (overdose).
  • Turning Point: Queen Victoria used chloroform during childbirth in 1853, making it socially acceptable.
  • John Snow: Invented the chloroform inhaler (1848) to regulate dosage, making it safer.

Worked example

Question

Explain two reasons why the use of chloroform was opposed in the mid-19th century.

Solution

One reason was religious objection. Some believed that pain, particularly in childbirth, was God's will, and relieving it was sinful. A second reason was medical safety. Early use of chloroform was unregulated, and it was easy to overdose a patient, leading to sudden death, as seen in the case of Hannah Greener.

Common pitfalls

  • Confusing anaesthetics (pain relief) with antiseptics (infection control).
  • Thinking anaesthetics immediately made surgery safer; they actually led to the 'Black Period' of higher death rates.

Prerequisites

  • Surgery barriers (Pain)
  • Chemical industry
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