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GCSE Biology 01 — Cell Biology, Transport & Health

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Topics include Cell Structure & Microscopy, Cell Division & Stem Cells, Transport in Cells, Cell Organisation & Specialisation, Digestion & Enzymes, Respiration & Exercise, The Human Circulatory System, and Gas Exchange & Lungs.

Biology EN
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Cell Structure & Microscopy

The fundamental differences between eukaryotic and prokaryotic cells, organelle functions, and the use of microscopy to view them.

Key points

  • Eukaryotes (plants, animals, fungi) have a nucleus and membrane-bound organelles; Prokaryotes (bacteria) are smaller, lack a nucleus, and have DNA in loops/plasmids.
  • Key organelles: Nucleus (DNA), Mitochondria (respiration), Ribosomes (proteins), Chloroplasts (photosynthesis, plants only).
  • Magnification formula: Magnification=Image sizeActual sizeMagnification = \frac{\text{Image size}}{\text{Actual size}}.
  • Electron microscopes offer higher magnification (×2,000,000\times 2,000,000) and resolution (0.2nm0.2nm) than light microscopes.
  • Unit conversions: 1mm=1000μm1mm = 1000\mu m; 1μm=1000nm1\mu m = 1000nm.

Worked example

Question

A mitochondrion has an actual length of 2μm2\mu m. The image size under a microscope is 10mm10mm. Calculate the magnification.

Solution

1. Convert units to match: 10mm=10,000μm10mm = 10,000\mu m.
2. Formula: M=I/AM = I / A.
3. Substitute: 10,000/2=×500010,000 / 2 = \times 5000.

Common pitfalls

  • Thinking bacteria have a nucleus (they don't).
  • Confusing cell wall (support) with cell membrane (transport control).
  • Forgetting to convert millimetres (mm) to micrometres (µm) in calculations.

Prerequisites

  • Basic units of measurement (mm, cm)
  • Concept of living things vs non-living
Further resources
  • Microscopy and Cells

    Clear review of cell structures and microscopy techniques.

    BBC Bitesize · article